Phosphate processing enzymes are crucial to the majority of the biochemical processes that all living cells depend on, including signal transduction, gene regulation, metabolism and energy transfer. 

However, it is not well understood how biological systems fine-tune the catalytic rates of phosphate transfer and hydrolysis reactions in order to achieve their precise function. 

We are particularly interested in the context of forming various assemblies through protein-protein, protein-nucleic acid, or importantly, protein-metal ion interactions using Mg.